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Sabine Costagliola

PI, Senior Research Associate FNRS
IRIBHM vice director

(scostag@ulb.ac.be)
phone # +32(0)2 555 6085

Sabine Costagliola completed a PhD in immunology at the Université Aix Marseille II (France) in 1991 and a PhD in Biomedical Science at ULB in 2000.  She obtained a permanent position at FNRS as Research Associate in 2000.  She is group leader and vice director of IRIBHM (Institut de Recherche Interdisciplinaire en Biologie Humaine et Moleculaire).

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Lab Manager :

Véronique Janssens

(verojans@ulb.ac.be
phone # +32(0)2 555 4197

Véronique studied at the “Athénée des Pagodes” obtained her CESS (option Latin – math) in 1994. She followed the first year of pharmacology at the “Université Libre de Bruxelles” (ULB). From 1995 to 1998, she performed a graduate in Medical Biology in “Institute Paul Lambin” (UCL) (assay: “Huntington chorea”) and obtained her diploma as technician of laboratories. In 1998, she started to work in Sabine Costagliola lab as lab technician and she obtained a permanent position at ULB in 2003. In 2013, she obtained a career advancement at ULB after a competitive examination and an essay entitled : “Zebrafish: a new biomedical research tool at ULB?”. Véronique is our lab manager.

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Postdocs :

Bárbara Fonseca
Bárbara Fonseca graduated in Biomedical Sciences at Fluminense Federal University (2010), followed by a Master’s degree in Cell and Developmental Biology at Federal University of Rio de Janeiro (2013), both in Brazil. She obtained a Ph.D. degree in Cell and Developmental Biology in 2017, at Pierre et Marie Curie University, in Paris (France). Currently, she is a postdoctoral researcher at IRIBHM-ULB, working on in vitro models of thyroid development.

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Olivier Monestier
Olivier Monestier completed his PhD in genomics and molecular genetics at the University of Limoges in 2012, under the supervision of Professor Véronique Blanquet (Animal Molecular Genetics Unit, Limoges, France). During his thesis, he developed and characterized mouse models associated with hypermuscular phenotype, notably some lines overexpressing the WFIKKN2 gene. From 2012 to 2015, he worked on the function and molecular evolution of TGFB proteins implicated in mammal reproduction as a postdoctoral researcher at the GenPhySE laboratory in the French National Institute for Agricultural Research (INRA) center of Toulouse (France) and then, as a research and teaching assistant at the University of Limoges. From 2015 to 2017, he worked on the molecular mechanisms of muscle stem cells fusion in fish as a postdoctoral researcher at the Fish Physiology and Genomics Institute in the Growth and Flesh Quality group lead by Jean-Charles Gabillard. Since 2017, he has been a postdoctoral researcher at the IRIBHM in the laboratory of Sabine Costagliola working on the generation of in vitro models of thyroid cancer.

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Mírian Romitti

Graduated in Biomedical Sciences from University of Cruz Alta, Brazil, 2008. Master (2012) and PhD (2014) in Biomedical Sciences: Endocrinology from University Federal of Rio Grande do Sul, Brazil. Postdoctoral researcher at Sabine Costagliola´s Lab, IRIBHM, ULB, Belgium from 2014 to 2017. Currently Chargé de Recherche FNRS.

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PhD Students:

Sabrina Ascenzo
Sabrina received a Master in biochemistry, molecular and cellular biology from Université Libre de Bruxelles (ULB) in 2013. After an end of study internship in the Lab of Sabine Costagliola, she decided to start a PhD thesis as a research fellow of FNRS/FRIA. The aim of her thesis was to figure out the role of Hhex along the thyroid development using an In vitro differentiation protocol starting from mESC associated with a protocol to invalidate genes “à la carte” in a mESC line.

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Cindy Barbée
Cindy studied at the “Athénée Royal de Péruwelz” from 2003 to 2009 to obtain her CESS with scientific orientation (strong math and sciences) where she obtained the prizes of Mathematics and Chemistry. She the obtained her Bachelor’s degree in Biomedical Sciences in 2012 at the University of Mons (Université de Mons-Hainaut) with distinction. Her master’s degree in Biomedical Sciences was obtained in 2014 at the university of Brussels (Université Libre de Bruxelles) with the highest honour. Since 2014, she is PhD student (F.R.S-FNRS Aspirant) at IRIBHM where she works on the mechanisms allowing the generation of functional thyroid tissue from murine embryonic stem cells by generating KO stem cell lines with TALEN and CRISPR technologies.

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Sandra Coppens
MD, specialization in neurology (2011), in pediatric neurology (2013) at ULB.  Interuniversity degree in myology in 2013 (Paris-Descartes University), interuniversity certificate in genetics in 2016 (Belgian Society of Human Genetics) Resident in pediatric neurology and pediatric consultations at the Neuromuscular Reference Center at Hospital Erasme and HUDERF from 2013 to 2017. PhD student at IRIBHM since 2015 (funded by the Fond Erasme and the Belgian Kids Fund). Title of the PhD thesis: Identification of genetic causes of myopathies through an integrated approach to in-depth phenotypic analysis, exome sequencing and gene knockdown in zebrafish

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Eleonore Dupuis
Eleonore joined IRIBHM for a master thesis in September 2014 in Wittamer Lab. She graduated for her master in June 2015 and joined the Costagliola Lab for a PhD funded by the Belgian Kids Fund. Her research project focused on zebrafish models to study the molecular networks of the myotubularin / amphiphysin / dynamin pathway involved in centronuclear myopathies

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Pierre Gillotay
Pierre graduated from Lycée Henriette Dachsbeck in June 2010 with a “latin-science” formation. He entered ULB to study biomedical sciences in September 2010 and got his bachelor degree in June 2013. After starting a master’s degree in biomedical sciences in September 2013, he joined the lab for a master thesis in September 2014 working on the impact of vascular development in thyroid organogenesis. He graduated for his master in June 2015 and stayed in the lab for a PhD after getting a FRIA fellowship in October 2015. His current work in mainly focused on understanding the fine molecular tuning of thyroid organogenesis using the Crispr-Cas9 technology.

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Benoît Haerlingen

Benoit completed his bachelor degree in biomedical sciences at the University of Namur in 2010 and a master in cellular and molecular biology at the Free University of Brussels in 2012. Since October 2012 he is PhD student in Costagliola lab and his research project focuses on cellular interactions between the thyroid and the heart in the developing embryo.