Welcome to the Costagliola Lab

With pluripotent stem cells and zebrafish as experimental models, our research uses state-of-the-art methods for precision genome editing  (Crispr/Cas) to model congenital diseases such as congenital hypothyroidism (thyroid) or centronuclear myopathies (skeletal muscle).

Our goal is to offer new diagnostic tools by completing the panel of candidate genes for these pathologies and to propose new therapeutic options.